My next best option is to enroll in a clinical trial that is testing new drugs specifically targeted at the T790M mutation. I am currently seeking trial sites in the Midwest, but travel will be difficult and costs may not be covered. Best option, my oncologist at Mayo has submitted a "compassionate use" request to AstraZeneca and the FDA for the singular use of AZD 9291 in my treatment.
I can't imagine the FDA will have a response in my lifetime, but ...what the heck, keep your digits crossed.
Overall, my quality of life stays good. I don't have much energy but I enjoy each day on "slow spin". My left eye is getting more difficult but I continue to read books and compare notes with Book Club members (email me if you want to join). Brigit is out of the hospital and recovering nicely. Rocket Dog just learned to fetch, which has been great fun. Pic of Rocket "post fetch".